DNA replication, DNA replication or DNA synthesis, cell division Prior
to double-stranded DNA'S copy the process of. Copied new DNA strands are
almost entirely the same, but from time to time due to copying errors
çoğalmadaki excellent not (see mutation), and resulting in both an old
and a spiral new made from yarn. This semi-conservative replication is
called. DNA replication process consists of three phases: initiation,
replication and
termination
Initiation
Starting several factors alamasında replication center'What is
collected. DNA replication in the center opens, the drop-down yarns are
partially a "replication bubble" form, a replication at both ends fork
found. Each enzyme group center runs away and moves to open the DNA
strands new yarn synthesis. Enzymes involved in this stage,
collectively, the "pre-replication complex is called. They are:
Helicase: DNA leads.Primaz: Required for DNA replication RNA "Primer"
strands synthesis. DNA haloenzim: The real growth in process a
collection of enzymes that perform
The proliferation of DNA polymerase process When it comes to the end
operation parallel Due to the lack of another problem arises: yarn trim
the 5 'end of the RNA primer strand connect to not enough space, so that
the DNA polymerase Connect The end of the copy, it will be impossible.
Solution of the problem in bacteria (or prokaryoticLarda) is very
easy: The circular structure of DNA in these organisms, so that the DNA
of a "tip" there. More complex eukaryoticLarda this "clever" is solved.
Telomere Every living thing is fixed according to the syntax of the ends
of DNA, called nucleotides (human 5 'GGGTTA 3') and in this short
sequence is repeated thousands of times. Also telomerase enzyme along
with the name corresponding to the telomere repeat sequence is a short
strand of RNA primer. Telomerase DNA replication process telomere at the
end of Connect carried on their own using the primer strand extends
telomeres. Thus, telomere RNA lining Connect copy, it is possible, but
the telomerase gene to prolong the long strands of DNA strand opposite
the other remains. This is a long remaining "single strand" in some
proteins help bent DNA end in itself creates a small ring. Ring become
not exposed to enzymes break down due to receipt of single-stranded DNA
molecules. The final stage of the copying errors that may have occurred
during the synthesis of DNA is determined by reading some enzimlerce, if
you have copied the wrong nuclease defective parts enzyme called DNA
breaks, DNA polymerase then fills in the gaps.
Figure 101: DNA helix stabilization to prevent the arms from each other
leaving again dolanmalarını enzymes (HSE) fixed amounts of both arms. In
the center, showing a separation of the DNA arms.
Figure 102: After leaving the two DNA polymerase enzymes that are
missing in both halves of the arm, complete with materials present
environment.
As is known, the cells divide and multiply. So what happens to DNA as a
result of this division? There is a single chain of DNA in the cell.
However, the newly formed cell will also need a DNA. To resolve this
deficit every stage of the process occurs in a separate a series of
miracle. As a result, a copy of the DNA of the cell division shortly
before the new cell is created and transferred.
DNA to replicate itself is divided into two parts, before the mutual.
This event takes place is quite an interesting way. Structure of the
middle of the DNA molecule resembles a spiral staircase, by an enzyme
called DNA helicase, is divided into two like a zipper. Stabilization of
the helix of DNA enzymes to prevent the arms from each other leaving
again dolanmalarını fixed amounts of both arms. (Figure 101)
Now divided into two halves of DNA. Both halves of the part that is
missing in (equivalents) present in the materials is completed.
Shortcomings in the completion work is carried out by DNA polymerase.
Thus, the two new DNA molecules are produced. (Figure 102)
Match several times during the emergence of new DNA molecules are
controlled by the controller enzymes. If you have made a mistake-that
these errors are detected and corrected immediately-may be crucial.
Correct password instead kopartılıp actually brought and mounted. All
these operations are made so that at a dizzying pace, while generating
up to 3,000 digits of nucleotide enzymes in charge of all these steps
and should be checked several times by the corrections made. (Figure
103)
Produced new DNA molecule, as a result of external influences can be
made more errors than normal. This time, the cell ribosomes, DNA, DNA
repair enzymes begin to produce in accordance with the orders. Thus, the
DNA will be protected and shall ensure the continuation of the lineage.
(Figure 104)
Here is the whole day, you never know when your life to continue without
any problems in your body admirable thoroughness and responsibility
made in the understanding of the numerous procedures and controls,
measures are taken. Everyone is completely and successfully fulfill the
task. Here is the smallest number of atoms and molecules of the Almighty
Allah, the greatest of our lives and the beautiful healthy In order to
maintain a service, has given way.
Biriyse most admirable aspects of this topic, as well as the structure
of DNA that controls both the production of these enzymes, according to
the information stored in DNA and proteins, DNA is made of the orders
and control. In the center there is intertwined so great that a system,
consisting of such a system gradually becomes in any way, this is not
possible by chance. Because the enzyme is DNA to the DNA of the enzyme
to be, that is for both of the cell, membrane, there must be complete
until all the other complex organelles.
Succession of organisms so-called "useful coincidences" as a result of
"gradual" claiming to have developed the theory of evolution, as in many
aspects than the above-mentioned before that we have DNA or enzymes
that are now in the face of unanswered questions. DNA and the enzyme are
required to have at the same time, which put forward the theory of
evolution is an impossible dream of the realization of mechanisms.
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